Onycholysis Associated With Capecitabine in Combination With Irinotecan in Two Patients With Colorectal Cancer
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چکیده
منابع مشابه
Onycholysis associated with capecitabine in combination with irinotecan in two patients with colorectal cancer.
Onycholysis, or the separation of the nail from its bed, is a non–lifethreatening toxicity, but one that may impair function and be visibly unpleasant. Anthracyclines and taxanes, alone or in combination, are the cytotoxic drugs most frequently associated with onycholysis (1,2). During the last year, we have treated 36 patients with metastatic colorectal cancer with an irinotecan–capecitabine c...
متن کاملCapecitabine/irinotecan combination regimens in colorectal cancer.
Capecitabine (Xeloda) and irinotecan (CPT-11, Camptosar) both have demonstrated single-agent activity in patients with colorectal cancer. In an analysis of pooled results of two phase III studies, capecitabine provided advantages over intravenous fluorouracil (5-FU) plus leucovorin in patients with metastatic colorectal cancer. In another analysis, metastatic colorectal cancer patients who rece...
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ژورنال
عنوان ژورنال: JNCI Journal of the National Cancer Institute
سال: 2003
ISSN: 0027-8874,1460-2105
DOI: 10.1093/jnci/djg034